This diagnostic assay identifies the presence of particular immunoglobulins that focus on a protein important for vitamin B12 absorption. These antibodies intervene with the binding of vitamin B12 to this important protein, a obligatory step for its uptake within the small gut. For example, a constructive consequence suggests the immune system is attacking this protein, hindering correct B12 absorption.
Detecting these antibodies is important as a result of it will possibly point out the presence of pernicious anemia, a situation attributable to vitamin B12 deficiency as a consequence of impaired absorption. Early identification by this testing permits for well timed intervention with B12 supplementation, stopping doubtlessly irreversible neurological injury and different issues related to continual deficiency. Its implementation has improved the diagnostic accuracy of pernicious anemia, distinguishing it from different causes of B12 deficiency.
