The detectability of psilocybin, the psychoactive compound in sure fungi, via customary drug screening strategies is proscribed. Routine drug exams typically don’t embody particular assays for psilocybin or its metabolite, psilocin. For instance, a regular five-panel drug check screens for substances like amphetamines, cocaine, opioids, phencyclidine (PCP), and tetrahydrocannabinol (THC), none of that are associated to psilocybin.
The first motive these substances aren’t routinely screened for lies of their fast metabolism and elimination from the physique, in addition to the comparatively excessive value and complexity of particular assays. Traditionally, drug testing panels have targeted on substances with increased charges of abuse and longer detection home windows. Moreover, psilocybin’s Schedule I classification impacts analysis and improvement of available and cost-effective testing strategies.